Products for Research Use Only

RSRC1 Antibody

CAT: 0223-5607-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-5607-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RSRC1 Antibody: The arginine/serine-rich coiled-coil 1 protein (RSRC1) was initially identified as a non-snRNP splicing factor that has a role in both the constitutive and alternative splicing of pre-mRNA molecules. In cellular nuclear extracts immunodepleted of RSRC1, the second step of pre-mRNA splicing is blocked; recombinant RSRC1 is able to restore splicing activity. RSRC1 has also been reported to be associated with schizophrenia as well as a unique marker of bone marrow-derived stem cells that also express the cdc34 marker.
NCBI Gene ID
51319
Swiss Prot
Q96IZ7
Accession Number
NP_057709
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
RSRC1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Buffer
RSRC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
RSRC1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
RSRC1
NCBI Official Name
Arginine/serine-rich coiled-coil 1
NCBI Organism
Homo sapiens
Background Reference 01
Cazalla D, Newton K, and Caceres JF. A noel SR-related protein is required for the second step of pre-mRNA splicing. Mol. Cell. Biol.2005; 25:2969-80.
Background Reference 02
Potkin SG, Turner JA, Fallon JA, et al. Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia. Mol. Psych.2009; 14:416-28.
Background Reference 03
Zhang QH, Ye M, Wu XY, et al. Cloning and functional analysis of cDNAs with open reading frames for 300 previously unidentified genes expressed in CD34+ hematopoietic stem/progenitor cells. Genome Res./i> 2008; 18:640-3.
Other Product Names
RSRC1 Antibody: BM-011, SFRS21, SRrp53, SRRP53, BM-011SRrp53
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
38488727
Physical Properties
Liquid