Beta-actin Antibody

CAT: 0223-5005-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-5005-01Size:0.02 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Beta-actin Antibody: Actins are highly conserved proteins that are involved in cell motility, structure and integrity, processes that are crucial for tissue development and the development of organism. The actin cytoskeleton is one of the principal drivers of cell motility and is capable of responding to complex signaling cascades. Recent evidence suggests that it may play key roles in regulating apoptosis and aging. Beta actin is one of six different actin isoforms which have been identified. Like GAPDH, beta-actin is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
NCBI Gene ID
60
Swiss Prot
P60709
Accession Number
AAH02409
Host
Chicken
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
Beta-actin Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Sheep: (100%), Rabbit: (100%), Pig: (100%), Horse: (100%), Chicken: (100%), Guinea pig: (100%), Bovine: (100%)
Buffer
Beta-actin Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Beta-actin antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgY
Symbol
ACTB
NCBI Official Name
Actin, beta
NCBI Organism
Homo sapiens
Background Reference 01
Lambrechts A, Van Troys, M and Ampe C. The actin cytoskeleton in normal and pathological cell motility. Int. J. Biochem. Cell Biol.2004; 36:1890-909.
Background Reference 02
Gourlay CW and Ayscough KR. The actin cytoskeleton: a key regulator of apoptosis and ageing? Nat. Rev.2005; 6:583-9.
Other Product Names
Beta-actin Antibody: BRWS1, PS1TP5BP1, Actin, cytoplasmic 1, Beta-actin
Tested Applications
ELISA, WB
Protein ID
12803203
Physical Properties
Liquid

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