Actin Antibody

• Background:

  Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. ACTB/ACTC are nonmuscle cytoskeletal actins and major constituents of the contractile apparatus. Defects in ACTB are a cause of juvenile-onset dystonia. Defects in ACTC have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC) .

• NCBI Gene ID:

  70

• Swiss Prot:

  P68032

• Accession Number:

  P68032

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Actin (ACTB/ACTC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the Central region of human Actin (ACTB/ACTC) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: C. Elegans, Drosophila, Xenopus, Chicken, Bovine, Mouse, Rabbit, Rat, Zebrafish, Hamster, Monkey, Pig, Yeast

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  42 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ACTC1

• NCBI Official Name:

  Actin, alpha cardiac muscle 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Villebeck, L., Biochemistry 46 (44), 12639-12647 (2007)

• Background Reference 02:

  Avizienyte, E., Exp. Cell Res. 313 (15), 3175-3188 (2007)

• Background Reference 03:

  Bouldin, A.A., Muscle Nerve 35 (2), 254-258 (2007)

• Other Product Names:

  Actin, alpha cardiac muscle 1, Alpha-cardiac actin, ACTC1, ACTC

• Tested Applications:

  WB, IHC-P

• Protein ID:

  54036697

• Physical Properties:

  Liquid