Beta-Actin Recombinant Protein

• Background:

  Actins are ubiquitous globular and highly conserved proteins that are involved in various types of cell motility, structure, and integrity. Three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. ACTB is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.

• NCBI Gene ID:

  60

• Swiss Prot:

  P60709

• Accession Number:

  P60709

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Homeostasis, Signal Transduction, Other

• Buffer:

  Supplied as a 0.2 um filtered solution of 10mM TrisHCl, 0.1% TritonX-100, 2mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  42.8 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Actin, beta

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Actin Cytoplasmic 1, Beta-Actin, ACTB

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3