Actin Antibody

• Background :

  Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. ACTB/ACTC are nonmuscle cytoskeletal actins and major constituents of the contractile apparatus. Defects in ACTB are a cause of juvenile-onset dystonia. Defects in ACTC have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC) .

• NCBI Gene ID :

  70

• Swiss Prot :

  P68032

• Accession Number :

  P68032

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This Actin (ACTB/ACTC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human Actin (ACTB/ACTC) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: C. Elegans, Drosophila, Xenopus, Chicken, Bovine, Rabbit, Rat, Zebrafish, Hamster, Monkey, Pig, Yeast

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  42 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  ACTC1

• NCBI Official Name :

  Actin, alpha cardiac muscle 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Villebeck, L., Biochemistry 46 (44), 12639-12647 (2007) Avizienyte, E., Exp. Cell Res. 313 (15), 3175-3188 (2007) Bouldin, A.A., Muscle Nerve 35 (2), 254-258 (2007)

• Other Product Names :

  Actin, alpha cardiac muscle 1, Alpha-cardiac actin, ACTC1, ACTC

• Tested Applications :

  WB, IHC-P, IF

• Protein ID :

  54036697

• Physical Properties :

  Liquid