Products for Research Use Only
RegisterLogin

CUEDC1 Antibody

CAT: 0223-4829-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-4829-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CUEDC1 Antibody: The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Two isoforms of CUEDC1 exist due to alternative splicing events. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker.
NCBI Gene ID
404093
Swiss Prot
Q9NWM3
Accession Number
AAH56882
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
CUEDC1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1464 - Rat Liver Tissue Lysate
Concentration
1 mg/mL
Buffer
CUEDC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CUEDC1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
CUEDC1 antibody will not cross-react with CUEDC2.
Symbol
CUEDC1
Positive Control 2
Cat. No. 10-201 - Human Liver Tissue Slide
NCBI Official Name
CUE domain containing 1
NCBI Organism
Homo sapiens
Background Reference 01
Shih SC, Prag G, Francis SA, et al. A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. EMBO J.2003; 22:1273-81.
Background Reference 02
Ponting CP. Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction. Biochem. J.2000; 351:527-35.
Background Reference 03
Prag G, Misra S, Jones EA, et al. Mechanism of ubiquitin recognition by the CUE domain of Vps9p. Cell2003; 113:609-20.
Background Reference 04
Kang RS, Daniels CM, Francis SA, et al. Solution structure of a CUE-ubiquitin complex reveals a conserved mode of ubiquitin binding. Cell2003; 113:621-30.
Other Product Names
CUEDC1 Antibody: CUE domain-containing protein 1
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
34785153
Physical Properties
Liquid

Related Products

CatalogName
4829PCUEDC1 Peptide
79-772CUEDC2 Antibody
4839-01CUEDC2 Antibody
4839-01mgCUEDC2 Antibody
4839-002mgCUEDC2 Antibody
4839PCUEDC2 Peptide
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody

Alternative Products

CatalogName
70R-1277CUEDC1 antibody
A17855Anti-CUEDC1 Antibody
MBS9238511-01CUEDC1 Polyclonal Antibody
APR06507GPolyclonal CUEDC1 Antibody
NBP1-86417Rabbit Polyclonal CUEDC1 Antibody
TA344146CUEDC1 Rabbit Polyclonal Antibody
GTR18993665CUEDC1 Antibody Blocking Peptide
MBS3206415-01CUEDC1 antibody - middle region
MBS200882-01CUEDC1
GTR18914468CUEDC1 Peptide

Popular Products