BMP15 Antibody

• Background:

  BMP15 Antibody: BMP15, or GDF9B is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily that are involved in embryonic development and adult tissue homeostasis. BMP15 is expressed exclusively in the oocyte. It is an oocyte-specific growth/differentiation factor that may be involved in oocyte maturation and follicular development. Defects in BMP15 are the cause of ovarian dysgenesis type 2. BMP15 could be used as an oogenesis marker to track human amniotic fluid stem cells differentiation into the oocyte-like cells.

• NCBI Gene ID:

  9210

• Swiss Prot:

  O95972

• Accession Number:

  NP_005439

• Host:

  Rabbit

• Reactivity:

  Human

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Stem Cell

• Purification:

  BMP15 Antibody is affinity chromatography purified via peptide column.

• Positive Control:

  Cat. No. 10-635 - Human Prostate Tissue Slide

• Concentration:

  1 mg/mL

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse: (89%), Sheep: (83%), Bovine: (83%)

• Buffer:

  BMP15 Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  BMP15 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  IgG

• Symbol:

  BMP15

• NCBI Official Name:

  Bone morphogenetic protein 15

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Massague J. The transforming growth factor-beta family. Ann. Rev. Cell. Biol. 1990; 6:597-641

• Background Reference 02:

  Aaltonen J, Laitinen MP, Vuojolainen K, et al. Human growth differentiation factor 9 (GDF-9) and its novel homolog GDF-9B are expressed in oocytes during early foliculogenesis. J. Clin. Endocrinol. Metab. 1999; 84:2744-50.

• Background Reference 03:

  Laitinen M, Vuojolainen K, Jaatinen R, et al. A novel growth differentiation factor-9 (GDF-9) related factor is coexpressed with GDF-9 in mouse oocytes during folliculogenesis. Mech. Dev. 1998; 78:135-40.

• Background Reference 04:

  Galloway SM, Gregan SM, Wilson T et al. Bmp15 mutations and ovarian function. Mol. Cell Endocrinol. 2002; 191:15-8

• Other Product Names:

  BMP15 Antibody: ODG2, POF4, GDF9B, Bone morphogenetic protein 15, BMP-15

• Tested Applications:

  ELISA, IHC-P

• Protein ID:

  257743454

• Physical Properties:

  Liquid