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BMP agonist 2

CAT: 0804-HY-158203-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-158203-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMP agonist 2 (derivative I-9) is a potent bone-inducing cytokine. BMP agonist 2 promotes bone tissue production by increasing the proportion and activity of osteoblasts. BMP agonist 2 promotes osteoblast proliferation and differentiation through the BMP2-ATF4 signaling axis, in which ATF4 is a transcription factor closely related to osteoblast differentiation and bone formation. BMP agonist 2 can be used in the study of senile osteoporosis (SOP) [1].
CAS Number
1438900-88-9
UNSPSC
12352005
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bmp-agonist-2.html
Purity
99.26
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC2=CC=C(OC)C=C2O1)OCCN3CCOCC3
Molecular Formula
C16H19NO5
Molecular Weight
305.33
References & Citations
[1]Zhou Z, et al. Efficacy, Mechanism, and Structure–Activity Relationship of 6-Methoxy Benzofuran Derivatives as a Useful Tool for Senile Osteoporosis[J]. Journal of Medicinal Chemistry, 2023, 66 (3) : 1742-1760.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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