Ebp (NM_007898) Mouse Recombinant Protein

• Background:

  This gene encodes a transmembrane protein that localizes to the endoplasmic reticulum. This protein catalyses the conversion of delta8 to delta7 sterols, an important step in sterol biosynthesis. Mutations in this gene are responsible for the mouse tattered mutant phenotype. Tattered males are embryonic lethal, while heterozygous females have developmental defects. Deficiency of the related gene in human causes X-linked dominant chondrodysplasia punctata. [provided by RefSeq, May 2015]

• Synonyms:

  AI255399; m; mSI; P; Pabp; SI; Td

• Gene ID:

  13595

• UniProt:

  P70245

• Accession Number mRNA:

  NM_007898

• Chromosomal Location:

  X 3.7 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  26.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ebp

• Species:

  Mouse

• Protein ID:

  NP_031924

• Overview:

  Purified recombinant protein of Mouse phenylalkylamine Ca2+ antagonist (emopamil) binding protein (Ebp), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/13595

• Uniprot URL:

  https://www.uniprot.org/uniprot/P70245

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_007898

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_031924