Mmp2 (NM_008610) Mouse Recombinant Protein

• Background:

  This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme that hydrolyzes collagens, gelatins, laminin, fibronectin and elastin. Mice lacking the encoded protein exhibit suppressed angiogenesis and attenuated features of human multicentric osteolysis with arthritis including abnormal skeletal and craniofacial development. [provided by RefSeq, Feb 2016]

• Synonyms:

  Clg; Clg4a; Ge; GelA; MMP-; MMP-2

• Gene ID:

  17390

• UniProt:

  P33434, Q3UG07

• Accession Number mRNA:

  NM_008610

• Chromosomal Location:

  8 44.99 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  74.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Mmp2

• Species:

  Mouse

• Protein ID:

  NP_032636

• Overview:

  Purified recombinant protein of Mouse matrix metallopeptidase 2 (Mmp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/17390

• Uniprot URL:

  https://www.uniprot.org/uniprot/P33434

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_008610

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_032636