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Recombinant Human CTF1 Protein

CAT: 0882-PH0070M2Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PH0070M2Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cardiotrophin-1 (CT-1) is a cytokine. It is a cardiac hypertrophic factor of 21.5 kDa and a protein member of the IL-6 cytokine family.CT-1 is associated with the pathophysiology of heart diseases, including hypertension, myocardial infarction, valvular heart disease, and congestive heart failure.The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130) /leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-κB DNA -binding activities. CT-1 is highly expressed in the heart, skeletal muscle, prostate and ovary and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine.
Purity
Greater than 95% by SDS-PAGE
Form
Lyophilized
Buffer
0.2 μm filtered PBS, pH7.4
Storage Conditions
-70°C

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