Products for Research Use Only

EEF2K (Ser366) Antibody [APR33499G]

CAT: 0882-APR33499G-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0882-APR33499G-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EEF2K (Ser366) Antibody [APR33499G].
Synonyms
Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, 2.7.11.20, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, EEF2K
Gene Name
EEF2K
Gene ID
29904
UniProt
O00418
Applications
WB
Dilution
WB--1:2000
Function
Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.
Molecular Weight
82144
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=29904
Uniprot URL
https://www.uniprot.org/uniprot/O00418

UniProtKB · O00418

Eukaryotic elongation factor 2 kinase

EF2K_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00418
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EEF2K
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
eEF-2 kinase, eEF-2K
EC number
2.7.11.20
Processing
—
Secondary accessions
Q8N588
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Ligand

ATP-bindingCalciumNucleotide-binding

Molecular function

Calmodulin-bindingKinaseSerine/threonine-protein kinaseTransferase