EEF2K (NM_013302) Human Recombinant Protein

• Background:

  This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008]

• Synonyms:

  CaMKIII; eEF-2K; HSU93850

• Gene ID:

  29904

• UniProt:

  O00418

• Accession Number mRNA:

  NM_013302

• Chromosomal Location:

  16p12.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase

• Molecular Weight:

  82 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EEF2K

• Species:

  Human

• Protein ID:

  NP_037434

• Overview:

  Recombinant protein of human eukaryotic elongation factor-2 kinase (EEF2K)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/29904

• Uniprot URL:

  https://www.uniprot.org/uniprot/O00418

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_013302

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_037434