Mouse Eef2k Antibody (N-term) [APC00083G]

CAT: 0882-APC00083G-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APC00083G-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Tissue Location: Ubiquitously expressed. Particularly abundant in skeletal muscle and heart

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mouse Eef2k Antibody (N-term) [APC00083G].

Synonyms

Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, Eef2k

Gene Name

Eef2k

Gene ID

13631

UniProt

O08796

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.

Molecular Weight

81739

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=13631

Uniprot URL

https://www.uniprot.org/uniprot/O08796

UniProtKB · O08796

Eukaryotic elongation factor 2 kinase

EF2K_MOUSE · Mus musculus

View on UniProt ↗

Primary accession: O08796
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Eef2k
Protein existence: 1: Evidence at protein level
Organism: Mus musculus (Mouse)
Taxonomy ID: 10090
Alternative names: eEF-2 kinase, eEF-2K
EC number: 2.7.11.20
Processing: —
Secondary accessions: —

Protein keywords

PTM

AcetylationPhosphoprotein

Ligand

ATP-bindingCalciumNucleotide-binding

Molecular function

Calmodulin-bindingKinaseSerine/threonine-protein kinaseTransferase

Technical term

Reference proteome

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