USP22 Antibody (C-term) [AMM02471G]

• Background:

  Tissue Location: Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver

• Synonyms:

  Ubiquitin carboxyl-terminal hydrolase 22, Deubiquitinating enzyme 22, Ubiquitin thioesterase 22, Ubiquitin-specific-processing protease 22, USP22, KIAA1063, USP3L

• Gene Name:

  USP22

• Gene ID:

  23326

• UniProt:

  Q9UPT9

• Chromosomal Location:

  Nucleus {ECO:0000250|UniProtKB:Q5DU02}.

• Applications:

  WB

• Dilution:

  WB--1:500

• Form:

  Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

• Function:

  Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

• Molecular Weight:

  59961

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality USP22 Antibody (C-term) [AMM02471G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=23326

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UPT9