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Avenanthramide-C methyl ester

CAT: 0804-HY-138284-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-138284-01Size:500 µg
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Description
Avenanthramide-C methyl ester is an anti-inflammatory agent and NF-κB inhibitor that inhibits the secretion of pro-inflammatory factors. Avenanthramide-C methyl ester inhibits NF-κB activation by inhibiting IKK and IκB phosphorylation and inhibiting proteasome activity[1].
CAS Number
955382-52-2
UNSPSC
12352005
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/avenanthramide-c-methyl-ester.html
Solubility
10 mM in DMSO
Smiles
COC(C1=C(C=CC(O)=C1)NC(/C=C/C2=CC(O)=C(C=C2)O)=O)=O
Molecular Formula
C17H15NO6
Molecular Weight
329.30
References & Citations
[1]Guo W, et al. Avenanthramides, polyphenols from oats, inhibit IL-1beta-induced NF-kappaB activation in endothelial cells. Free Radic Biol Med. 2008 Feb 1;44 (3) :415-29.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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