Avenanthramide-C methyl ester

Avenanthramide-C methyl ester

• CAS Number: 955382-52-2
• UNSPSC Description: Avenanthramide-C methyl ester is an anti-inflammatory agent and NF-κB inhibitor that inhibits the secretion of pro-inflammatory factors. Avenanthramide-C methyl ester inhibits NF-κB activation by inhibiting IKK and IκB phosphorylation and inhibiting proteasome activity[1].
• Target Antigen: NF-κB
• Type: Reference compound
• Related Pathways: NF-κB
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/avenanthramide-c-methyl-ester.html
• Solubility: 10 mM in DMSO
• Smiles: COC(C1=C(C=CC(O)=C1)NC(/C=C/C2=CC(O)=C(C=C2)O)=O)=O
• Molecular Weight: 329.30
• References & Citations: [1]Guo W, et al. Avenanthramides, polyphenols from oats, inhibit IL-1beta-induced NF-kappaB activation in endothelial cells. Free Radic Biol Med. 2008 Feb 1;44(3):415-29.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported