PFI-90

• UNSPSC Description:

  PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased. PFI-90 has the potential for the antitumor activity. (patent WO2021101929A1).

• Target Antigen:

  Apoptosis; Histone Demethylase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Epigenetics

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pfi-90.html

• Smiles:

  O=C(C1=NC=CC=C1)NNC2=NC=CC=C2

• Molecular Weight:

  214.22

• References & Citations:

  [1]KHAN, Javed, et al. Inhibitors of histone demethylases (pfi-63 and pfi-90) for the treatment of cancer and for the inhibition of histone demethylase in cells. WO2021101929A1.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  53995-62-3