TT-232 (TFA)

• Description:

  TT-232 TFA (CAP-232 TFA) is an analogue of somatostatin. TT-232 TFA can induce apoptosis of pancreatic tumor cell lines, inhibit tyrosine kinase activity and stimulate tyrosine phosphatase activity in colon tumor cell lines. TT-232 TFA inhibits the proliferation of tumor cells, induces apoptosis of tumor cells and shows strong anti-tumor effects. TT-232 TFA can be used in the development of anti-tumor drugs and the study of apoptosis mechanism[1].

• Product Name Alternative:

  CAP-232 (TFA) ; TLN-232 (TFA)

• UNSPSC:

  12352005

• Target:

  Apoptosis; Somatostatin Receptor

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; GPCR/G Protein; Neuronal Signaling

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tt-232-tfa.html

• Smiles:

  O=C(N[C@H](C(N[C@@H]1C(N[C@H](C(N)=O)[C@H](O)C)=O)=O)CCCCN)[C@H](NC([C@@H](NC([C@H](CSSC1)NC([C@H](N)CC2=CC=CC=C2)=O)=O)CC(C=C3)=CC=C3O)=O)CC4=CNC5=CC=CC=C45.O=C(O)C(F)(F)F

• Molecular Formula:

  C47H59F3N10O11S2

• Molecular Weight:

  1061.16

• References & Citations:

  [1]Li H, et al. Synthesis, conformational analysis and bioactivity of Lan‐7, a lanthionine analog of TT‐232[J]. Journal of Peptide Science: An Official Publication of the European Peptide Society, 2000, 6 (1) : 26-35.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  [2703745-48-4]