LEF1 Recombinant Rabbit Monoclonal Antibody [JE52-28]

LEF1 Recombinant Rabbit Monoclonal Antibody [JE52-28]

• Description: Lymphoid enhancer-binding factor 1 (LEF1) is a protein that in humans is encoded by the LEF1 gene. It's a member of T cell factor/lymphoid enhancer factor (TCF/LEF) family. Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1). LEF1 is highly overexpressed and associated with disease progression and poor prognosis in B-cell chronic lymphocytic leukemia and other kinds of malignancies like colorectal cancer. It is also a promising potential drug target.
• Product Name Alternative: DKFZp586H0919 antibody FLJ46390 antibody LEF 1 antibody LEF-1 antibody Lef1 antibody LEF1_HUMAN antibody Lymphoid enhancer binding factor 1 antibody Lymphoid enhancer-binding factor 1 antibody T cell specific transcription factor 1 alpha antibody T cell-specific transcription factor 1-alpha antibody TCF 1 alpha antibody TCF1 alpha antibody TCF1-alpha antibody TCF10 antibody TCF1alpha antibody TCF7L3 antibody Transcription factor T cell specific 1 alpha antibody
• Abbreviation: LEF1
• CAS Number: 9000-83-3
• Swiss Prot: Q9UJU2 Human, P27782 Mouse, Q9QXN1 Rat
• Cellular Locus: Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human LEF1 aa 121-170 / 399.
• Isotype: IgG
• Clone: JE52-28
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: Jurkat cell lysate, mouse thymus tissue lysate, rat thymus tissue lysate, Jurkat, human lymph node tissue, human thymus tissue, human tonsil tissue, rat thymus tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IF-Cell: 1:500 ;IHC-P: 1:500-1:2,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 44 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes