MX69-102

MX69-102

• UNSPSC Description: MX69-102 (compound MX69-102) is an MDM-2/p53 inhibitor, inducing MDM2 degradation, resulting in p53 activation and cancer cell apoptosis. MX69-102 shows effective inhibition on xenografted human MDM2-overexpressing ALL in SCID mice.[1].
• Target Antigen: MDM-2/p53
• Type: Reference compound
• Related Pathways: Apoptosis
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mx69-102.html
• Smiles: O=C(C1=CC=CC(NS(=O)(C2=CC=C(C3=C2)NC([C@H]4[C@@H]3OCC4)C5=CC=C(C=C5)C(C(C)C)=O)=O)=C1)C
• Molecular Weight: 518.62
• References & Citations: [1]Liu T, et al. An MDM2 degrader shows potent cytotoxicity to MDM2-overexpressing acute lymphoblastic leukemia cells with minimal toxicity to normal cells/tissues. Cancer Lett. 2024 Aug 28;598:217126.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported