Products for Research Use Only
RegisterLogin

PPQ-102

CAT: 0804-HY-14179-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14179-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PPQ-102 (CFTR Inhibitor) is a reversible CFTR inhibitor that completely inhibits CFTR chloride currents (IC50 ~90 nM) . PPQ-102 is not affected by membrane potential-dependent cell allocation or blocking efficiency (uncharged at physiological pH) and effectively prevents cyst enlargement in polycystic kidney disease[1].
CAS Number
931706-15-9
Product Name Alternative
CFTR Inhibitor
UNSPSC
12352005
Hazard Statement
H302, H317
Target
CFTR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/PPQ-102.html
Purity
99.73
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CN1C(C2=C(C3=CC=CC=C3)N4C5=CC=CC=C5NC(C6=CC=C(C)O6)C4=C2N(C)C1=O)=O
Molecular Formula
C26H22N4O3
Molecular Weight
438.48
Precautions
H302, H317
References & Citations
[1]Tradtrantip L, et al. Nanomolar potency pyrimido-pyrrolo-quinoxalinedione CFTR inhibitor reduces cyst size in a polycystic kidney disease model. J Med Chem. 2009 Oct 22;52 (20) :6447-55.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-111026PPQ-581
HY-P991504-01LAE-102
HY-P991405EU-102
HY-133845CIL-102
HY-168537LB-102
HY-12220-01MM-102
HY-15732-01BGB-102
HY-120132KNI-102
HY-118858-01UCPH-102
HY-157912EGFR-IN-102

Alternative Products

CatalogName
T1874-01PPQ-102
MBS130413-01PPQ 102
A13000-2PPQ-102 2mg
A13000-25PPQ-102 25mg
A13000-100PPQ-102 100mg
A13000-50PPQ-102 50mg
A13000-10PPQ-102 10mg
A13000-5PPQ-102 5mg
A13000-1PPQ-102 1mg
A13000-10mM-DPPQ-102 10mM * 1mL in DMSO

Popular Products