CIL-102

• Description :

  CIL-102, an apoptosis inducer, is a MMP-2/MMP-9 inhibitor that decreases MMP-2/MMP-9 protein expression and mRNA levels. CIL-102 displays an anti-cancer activity[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; MMP

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Smiles :

  CC(C1=CC=C(NC2=C3C(OC=C3)=NC4=CC=CC=C24)C=C1)=O

• Molecular Formula :

  C19H14N2O2

• Molecular Weight :

  302.33

• References & Citations :

  [1]Liu WH, et al. CIL-102 induces matrix metalloproteinase-2 (MMP-2) /MMP-9 down-regulation via simultaneous suppression of genetic transcription and mRNA stability. Int J Biochem Cell Biol. 2012 Dec;44 (12) :2212-22.|[2]Huang WS, et al. CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45. PLoS One. 2017 Jan 9;12 (1) :e0168989.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  MMP-2; MMP-9

• CAS Number :

  [479077-76-4]