SIYNFEKL (TFA)

• UNSPSC Description:

  SIYNFEKL TFA is a variant of major MHC class I-restricted epitope SIINFEKL. SIYNFEKL TFA is an antigenic peptide, that can stimulate specific T cells in experimental settings to study the competitive interaction between T cell. SIYNFEKL TFA exhibits low affinity for the OT-I T cell receptor (TCR), and can be used for detection of CD8+ T cells[1].

• Target Antigen:

  Others

• Type:

  Peptides

• Related Pathways:

  Others

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/siynfekl-tfa.html

• Purity:

  99.92

• Solubility:

  H2O : ≥ 12.5 mg/mL

• Smiles:

  OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)CC2=CC=CC=C2)=O)=O)NC([C@H]([C@@H](C)CC)NC([C@@H](N)CO)=O)=O.O=C(C(F)(F)F)O.[x]

• Molecular Weight:

  1013.14 (free acid)

• References & Citations:

  [1]Burchill MA, et al., T cells compete by cleaving cell surface CD27 and blocking access to CD70-bearing APCs. Eur J Immunol. 2015 Nov;45(11):3140-9.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported