BMP-4

BMP-4

• CAS Number: 1629625-47-3
• UNSPSC Description: BMP-4 is a penetrating heparin-binding peptide with anti-inflammatory and anti-chondrogenic functions. In murine chondrocytes and macrophages, BMP-4 regulates the iNOS-IFN-IL6 signaling pathway to inhibit the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 in a dose-dependent manner, effectively suppressing inflammation and alleviating various arthritis symptoms[1].
• Target Antigen: COX; IFNAR; Interleukin Related
• Type: Peptides
• Related Pathways: Immunology/Inflammation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/bmp-4.html
• Smiles: OC([C@H](CC1=CN=CN1)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CS)NC([C@H](CC(N)=O)NC([C@H]2N(CCC2)C([C@H](CC(N)=O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
• Molecular Weight: 1308.52
• References & Citations: [1]Pathade V, et al. Emerging insights of peptide-based nanotherapeutics for effective management of rheumatoid arthritis. Life Sci. 2023 Jan 1;312:121257.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported