BMP-4

• UNSPSC Description:

  BMP-4 is a penetrating heparin-binding peptide with anti-inflammatory and anti-chondrogenic functions. In murine chondrocytes and macrophages, BMP-4 regulates the iNOS-IFN-IL6 signaling pathway to inhibit the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 in a dose-dependent manner, effectively suppressing inflammation and alleviating various arthritis symptoms[1].

• Target Antigen:

  COX; IFNAR; Interleukin Related

• Type:

  Peptides

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/bmp-4.html

• Smiles:

  OC([C@H](CC1=CN=CN1)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CS)NC([C@H](CC(N)=O)NC([C@H]2N(CCC2)C([C@H](CC(N)=O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  1308.52

• References & Citations:

  [1]Pathade V, et al. Emerging insights of peptide-based nanotherapeutics for effective management of rheumatoid arthritis. Life Sci. 2023 Jan 1;312:121257.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1629625-47-3