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MLS-573151

CAT: 0804-HY-113849-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113849-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC50 of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42[1][2].
CAS Number
10179-57-4
Product Name Alternative
MLS000573151
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mls-573151.html
Purity
99.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(N2N=C(C3=CC=CC=C3)CC2C4=CC=CC=C4)C=C1)(N)=O
Molecular Formula
C21H19N3O2S
Molecular Weight
377.46
Precautions
H302, H315, H319, H335
References & Citations
[1]Zurab Surviladze, et al. Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay. J Biomol Screen. 2010 Jan;15 (1) :10-20.|[2]Fan Mao, et al. Transcriptomic Evidence Reveals the Molecular Basis for Functional Differentiation of Hemocytes in a Marine Invertebrate, Crassostrea gigas. Front Immunol. 2020 May 27;11:911.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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