DP-b99

• Description:

  DP-b99 is a chelator of zinc and calcium ions that acts selectively within cell membranes and has neuroprotective properties in animal models of stroke.

• UNSPSC:

  12352005

• Target:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dp-b99.html

• Purity:

  95.0

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (CN (C1=CC=CC=C1OCCOC2=CC=CC=C2N (CC (OCCOCCCCCCCC) =O) CC (O) =O) CC (O) =O) OCCOCCCCCCCC

• Molecular Formula:

  C42H64N2O12

• Molecular Weight:

  788.96

• References & Citations:

  [1]Kalendarev T, Zupkovitz G, Ioffe V. The unusual gradient elution for reversed phase HPLC of a strong chelator as an active drug substance. J Pharm Biomed Anal. 2001;24 (5-6) :967-975. |[2]Diener HC, Schneider D, Lampl Y, Bornstein NM, Kozak A, Rosenberg G. DP-b99, a membrane-activated metal ion chelator, as neuroprotective therapy in ischemic stroke. Stroke. 2008;39 (6) :1774-1778.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 3

• CAS Number:

  222315-88-0