DP-b99

• Description :

  DP-b99 is a chelator of zinc and calcium ions that acts selectively within cell membranes and has neuroprotective properties in animal models of stroke.

• UNSPSC :

  12352005

• Target :

  Others

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/dp-b99.html

• Purity :

  95.0

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(CN(C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(OCCOCCCCCCCC)=O)CC(O)=O)CC(O)=O)OCCOCCCCCCCC

• Molecular Formula :

  C42H64N2O12

• Molecular Weight :

  788.96

• References & Citations :

  [1]Kalendarev T, Zupkovitz G, Ioffe V. The unusual gradient elution for reversed phase HPLC of a strong chelator as an active drug substance. J Pharm Biomed Anal. 2001;24 (5-6) :967-975. |[2]Diener HC, Schneider D, Lampl Y, Bornstein NM, Kozak A, Rosenberg G. DP-b99, a membrane-activated metal ion chelator, as neuroprotective therapy in ischemic stroke. Stroke. 2008;39 (6) :1774-1778.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 3

• CAS Number :

  [222315-88-0]