PPTN (mesylate)

CAT: 0804-HY-103055Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-103055Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PPTN mesylate is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a KB value of 434 pM. PPTN mesylate exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and immune activity[1].
CAS Number
[1160271-31-7]
UNSPSC
12352005
Target
P2Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pptn-mesylate.html
Smiles
O=C(C1=CC(C2=CC=C(C3CCNCC3)C=C2)=C4C=CC(C5=CC=C(C(F)(F)F)C=C5)=CC4=C1)O.CS(=O)(O)=O
Molecular Formula
C30H28F3NO5S
Molecular Weight
571.61
References & Citations
[1]Barrett MO, et al. A selective high-affinity antagonist of the P2Y14 receptor inhibits UDP-glucose-stimulated chemotaxis of human neutrophils. Mol Pharmacol. 2013 Jul;84 (1) :41-9.|[2]Lin J, et al. The P2Y14 receptor in the trigeminal ganglion contributes to the maintenance of inflammatory pain. Neurochem Int. 2019 Dec;131:104567.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-110322A-01PPTN
HY-110322-01PPTN (hydrochloride)
HY-70057A-01Safinamide (mesylate)
HY-14405A-01Casopitant (mesylate)
HY-13512-01Camostat (mesylate)
HY-103201A 80426 (mesylate)
HY-19475ATaprizosin (mesylate)
HY-135317DEmavusertib (mesylate)
HY-107191Sildenafil (Mesylate)
HY-101437A-01Ralfinamide (mesylate)

Alternative Products

CatalogName
MBS5774401PPTN Mesylate
M33073-01PPTN
MBS5806202PPTN hydrochloride
4862/10PPTN hydrochloride 10 mg
TRC-C184150-100MG(S)-Carnitine Mesylate, Mesylate Salt
TRC-C184125-25MG(S)-Carnitine Mesylate Isobutylester, Mesylate Salt
TRC-G407002-0.5MGGleevec-d8 Mesylate (Imatinib-d8 Mesylate)
268002-01S-Carnitine mesylate isobutylester, mesylate salt
A24177-5Befotertinib mesylate (D-0316 mesylate) 5mg
A24177-10Befotertinib mesylate (D-0316 mesylate) 10mg

Popular Products