Thalidomide-PEG1-OTs

CAT: 0804-HY-168222Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-168222Size:1 Each
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Description
Thalidomide-PEG1-OTs (Compound 5) is a ligand for E3 ligase, used for the synthesis of YD54 (HY-168221) [1].
CAS Number
[2850354-04-8]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thalidomide-peg1-ots.html
Smiles
O=C(N(C1CCC(NC1=O)=O)C2=O)C3=C2C=CC=C3OCCOS(C4=CC=C(C)C=C4)(=O)=O
Molecular Formula
C22H20N2O8S
Molecular Weight
472.47
References & Citations
[1]Kotagiri S, et al. Discovery of Novel, Potent and Orally Bioavailable SMARCA2 PROTACs with Synergistic Anti-tumor Activity in Combination with KRAS G12C Inhibitors. bioRxiv [Preprint]. 2024 Aug 26:2024.08.23.608456.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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