(S,R,S)-AHPC-PEG1-OTs

• Product Name Alternative:

  VH032-PEG1-OTs; VHL Ligand-Linker Conjugates 2; E3 ligase Ligand-Linker Conjugates 51

• UNSPSC Description:

  (S,R,S)-AHPC-PEG1-OTs is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 1-unit PEG linker used in PROTAC technology.

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugates-51.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@H]1N(C([C@@H](NC(COCCOS(C2=CC=C(C)C=C2)(=O)=O)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3

• Molecular Weight:

  686.84

• References & Citations:

  [1]Burslem GM, et al. Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-mediated Targeted Protein Degradation. Cancer Res. 2019 Jul 16. pii: canres.1236.2019.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported