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Lactic acid (potassium)

CAT: 0804-HY-B2227C-01Size: 50 gDry Ice: NoHazardous: No
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CAT#:0804-HY-B2227C-01Size:50 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lactic acid (DL-Lactic acid) potassium is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid potassium is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid potassium is an oncometabolite and has immune protective role of lactate in anti-tumor immunity[1][2]. Lactic acid also potassium has antimicrobial activity, which can be used as a food preservative[3].
CAS Number
996-31-6
Product Name Alternative
DL-Lactic acid (potassium) ; E-270 (potassium)
UNSPSC
12352300
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; Endogenous Metabolite; Hydroxycarboxylic Acid Receptor (HCAR)
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lactate-potassium.html
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
OC(C([O-])=O)C.[K+]
Molecular Formula
C3H5KO3
Molecular Weight
128.17
Precautions
H302, H315, H319, H335
References & Citations
[1]Lucia Longhitano, et al. Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence Phenotype. Int J Mol Sci. 2022 Dec 20;24 (1) :24.|[2]Qiang Feng, et al. Lactate increases stemness of CD8 + T cells to augment anti-tumor immunity. Nat Commun. 2022 Sep 6;13 (1) :4981. |[3]Sallam KI. Antimicrobial and antioxidant effects of sodium acetate, sodium lactate, and sodium citrate in refrigerated sliced salmon. Food Control. 2007 May;18 (5) :566-575.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
HCAR1

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