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Lactic acid (calcium)

CAT: 0804-HY-B2227A-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B2227A-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lactic acid (DL-Lactic acid) calcium is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid calcium is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid calcium is an oncometabolite and has immune protective role of lactate in anti-tumor immunity[1][2]. Lactic acid calcium also has antimicrobial activity, which can be used as a food preservative[3].
CAS Number
814-80-2
Product Name Alternative
DL-Lactic acid (calcium) ; E-270 (calcium)
UNSPSC
12352300
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; Endogenous Metabolite; Hydroxycarboxylic Acid Receptor (HCAR)
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lactate-calcium.html
Concentration
10mM
Purity
99.8
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL
Smiles
CC(O)C([O-])=O.[1/2].[Ca+2]
Molecular Formula
C3H6O3.1/2Ca
Molecular Weight
110.12
Precautions
H302, H315, H319, H335
References & Citations
[1]Lucia Longhitano, et al. Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence Phenotype. Int J Mol Sci. 2022 Dec 20;24 (1) :24.|[2]Qiang Feng, et al. Lactate increases stemness of CD8 + T cells to augment anti-tumor immunity. Nat Commun. 2022 Sep 6;13 (1) :4981. |[3]Sallam KI. Antimicrobial and antioxidant effects of sodium acetate, sodium lactate, and sodium citrate in refrigerated sliced salmon. Food Control. 2007 May;18 (5) :566-575.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
HCAR1

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