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Antibacterial agent 199

CAT: 0804-HY-125524Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-125524Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antibacterial agent 199 (Compound 2) is an activator for caseinolytic protease (ClpP) with a Kd of 0.7 μM. Antibacterial agent 199 exhibits antibacterial efficacy against Gram-positive strains Staphylococcus aureus, Streptococcus pneumoniae and Gram-negative strain Neisseria meningitidis, with MICs of 16, 0.5 and 0.5 μg/mL, respectively[1].
CAS Number
1629166-56-8
UNSPSC
12352005
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-199.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](C(N1[C@@H](CCC1)C(N(C)[C@H](C(N[C@@H](C)C(N2[C@H]3CCC2)=O)=O)C)=O)=O)COC3=O)[C@H](CC4=CC=CC=C4)NC(/C=C/C=C/C=C/C)=O
Molecular Formula
C37H48N6O8
Molecular Weight
704.81
References & Citations
[1]Goodreid JD, et al., Total synthesis and antibacterial testing of the A54556 cyclic acyldepsipeptides isolated from Streptomyces hawaiiensis. J Nat Prod. 2014 Oct 24;77 (10) :2170-81.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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