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LC3B rabbit pAb

CAT: 0855-ES20679-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES20679-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008]
Description
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008],
UniProt
Q9GZQ8
Swiss Prot
Q9GZQ8
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Protein of MAP LC3β
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; IHC
Dilution
WB: 1:1000-2000 IHC: 1:200-500 IF 1:200
Molecular Weight
14,16kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
14,16kD
Fragment
IgG
Subcellular Location
Cytoplasmic vesicle, autophagosome membrane ; Lipid-anchor . Endomembrane system ; Lipid-anchor . Mitochondrion membrane ; Lipid-anchor . Cytoplasm, cytoskeleton . Cytoplasmic vesicle . LC3-II binds to the autophagic membranes. LC3-II localizes with the mitochondrial inner membrane during Parkin-mediated mitophagy (PubMed:28017329) . Localizes also to discrete punctae along the ciliary axoneme. .
Other Product Names
MAP1LC3B; MAP1ALC3; Microtubule-associated proteins 1A/1B light chain 3B; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B light chain 3 B; MAP1A/MAP1B LC3 B; Microtubule-associated protein 1 light chain 3 beta
Gene ID (Human)
81631

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