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[Orn5]-URP (TFA)

CAT: 0804-HY-P1167ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1167ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
[Orn5]-URP TFA is a potent and selective pure antagonist of Urotensin-II receptor (UT), with an pEC50 of 7.24. [Orn5]-URP TFA displays no agonist activity[1][2].
UNSPSC
12352209
Target
Urotensin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/orn5-urp-tfa.html
Solubility
H2O
Smiles
OC(C(F)(F)F)=O.O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC1=O)CCCN)=O)CC2=CC=C(C=C2)O)=O)C(N[C@H](C(O)=O)C(C)C)=O)NC([C@@H](N)C)=O)=O)CC3=CC=CC=C3)N[C@H]1CC4=CNC5=CC=CC=C45
Molecular Formula
C48H62N10O10S2.xC2HF3O2
Molecular Weight
1003.20 (free acid)
References & Citations
[1]Diallo M, et, al. [Orn5]URP acts as a pure antagonist of urotensinergic receptors in rat cortical astrocytes. Peptides. 2008 May; 29 (5) : 813-9.|[2]David C, et, al. Structure-activity relationships and structural conformation of a novel urotensin II-related peptide. Peptides. 2004 Oct; 25 (10) : 1819-30.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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