Recombinant NQO1 Monoclonal Antibody

• Background:

  This gene is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 1-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD) . Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

• Abbreviation:

  NQO1

• UniProt:

  P15559

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human NQO1 Protein

• Target:

  NQO; DIA; NMOR; DHQU; DIA4; DTD; NMOR1; NMORI; QR1; NQO1; Azoreductase; Cytochrome b 5 reductase; DIA 4; Diaphorase (NADH/NADPH) ; Diaphorase (NADH/NADPH) (cytochrome b 5 reductase) ; Diaphorase 4; Dioxin inducible 1; DT diaphorase; DT-diaphorase; Menadione reductase; NAD (P) H dehydrogenase [quinone] 1; NAD (P) H dehydrogenase quinone 1; NAD (P) H menadione oxidoreductase 1 dioxin inducible; NAD (P) H quinone dehydrogenase 1; NAD (P) H: menadione oxidoreductase 1 dioxin inducible 1; NAD (P) H:menadione oxidoreductase 1; NAD (P) H:Quinone acceptor oxidoreductase type 1; NAD (P) H:quinone oxidoreductase 1; NAD (P) H:quinone oxireductase; NMOR 1; NMOR I; NQO 1; Phylloquinone reductase; QR 1; Quinone reductase 1

• Clonality:

  Monoclonal

• Clone:

  5B11

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Signal Transduction; Metabolism

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  31 kDa

• Observed Molecular Weight:

  31 kDa

• Isotype:

  IgG