NQO1 Antibody

• Description:

  This gene is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD) . Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [RefSeq]

• Specifications:

  Western blot: 1:1000-1:5000, Immunofluorescence: 1:50-1:200, Immunohistochemistry (FFPE) : 1:50-1:200

• UniProt:

  P15559

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide specific to human NQO1 was used as the immunogen for the NQO1 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Clone:

  AAOB-14

• Type:

  Recombinant

• Applications:

  WB, IF, IHC-P

• Purity:

  Affinity purified

• Format:

  Purified

• Buffer:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution:

  Store the NQO1 antibody at -20oC.

• Limitations:

  This NQO1 antibody is available for research use only.

• Storage Conditions:

  Store the NQO1 antibody at -20°C.

• Formulation:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes:

  Optimal dilution of the NQO1 antibody should be determined by the researcher.

• CAS Number:

  9000-83-3

• Image Legend:

  Western blot testing of human SH-SY5Y cell lysate with NQO1 antibody. Predicted molecular weight ~30 kDa.