Hit 14

• UNSPSC Description:

  Hit 14 is an inhibitor for C-X-C chemokine receptor type 4 (CXCR4) with IC50 of 254 nM. Hit 14 inhibits the migration and invasion of cell MDA-MB-231. Hit 14 inhibits the Akt phosphorylation, exhibits anti-inflammatory activity, and ameliorateds the ear swelling and damage in mouse models[1].

• Target Antigen:

  Akt; CXCR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Immunology/Inflammation;PI3K/Akt/mTOR

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/hit-14.html

• Smiles:

  O=S(C1=CC=C(OC2=CC=C(S(=O)(NCC3OCCC3)=O)C=C2)C=C1)(NCC4OCCC4)=O

• Molecular Weight:

  496.60

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  440338-68-1