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A 83-01 (GMP)

CAT: 0804-HY-10432G-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-10432G-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A 83-01 (GMP) is A 83-01 produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. A 83-01 is a potent ALK4/5/7 inhibitor[1][2].
CAS Number
909910-43-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Anaplastic lymphoma kinase (ALK)
Type
GMP Small Molecules
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/a-83-01-gmp.html
Purity
99.30
Solubility
10 mM in DMSO
Smiles
S=C(N1N=C(C2=NC(C)=CC=C2)C(C3=CC=NC4=CC=CC=C34)=C1)NC5=CC=CC=C5
Molecular Formula
C25H19N5S
Molecular Weight
421.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Guan J, et al. Chemical reprogramming of human somatic cells to pluripotent stem cells. Nature. 2022 May;605 (7909) :325-331.|[2]Liu J, et al. Efficient episomal reprogramming of blood mononuclear cells and differentiation to hepatocytes with functional drug metabolism. Exp Cell Res. 2015 Nov 1;338 (2) :203-13.
Shipping Conditions
Dry Ice
Storage Conditions
-20°C, protect from light
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported

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