RegisterLogin

DBCO-NHS ester 2

CAT: 0804-HY-115524-01Size: 5 mgDry Ice: NoHazardous: No
CAT#: HY-115524-01Size: 5 mg
Selected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC) . DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
CAS Number
[1384870-47-6]
Product Name Alternative
PQQ; Methoxatin
UNSPSC
12352203
Hazard Statement
H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-nhs-ester-2.html
Purity
99.69
Solubility
DMSO : 14.29 mg/mL (ultrasonic)
Smiles
O=C1CCC(N1OC(CCCCC(N2C3=CC=CC=C3C#CC(C=CC=C4)=C4C2)=O)=O)=O
Molecular Formula
C25H22N2O5
Molecular Weight
430.45
Precautions
H315, H319, H335
References & Citations
[1]Tang F, et al. Chemoenzymatic synthesis of glycoengineered IgG antibodies and glycosite-specific antibody-drug conjugates. Nat Protoc. 2017 Aug;12 (8) :1702-1721.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported

Related Products

CatalogName
HY-42973-01DBCO-NHS ester
HY-140271-01DBCO-PEG1-NHS ester
HY-140272-01DBCO-PEG4-NHS ester
HY-151835-01DBCO-PEG24-NHS ester
HY-140274-01DBCO-PEG12-NHS ester
HY-126885-01DBCO-PEG5-NHS ester
HY-115545-01DBCO-NHS ester 3
HY-156507-01DBCO-PEG3-NHS ester
HY-W879040Sulfo-DBCO-NHS ester
HY-140273-01DBCO-PEG8-NHS ester

Alternative Products

CatalogName
TRC-D194965-100MGDBCO-NHS Ester
MBS3601436-01DBCO-NHS ester
M11436-01DBCO-NHS ester
T15067-01DBCO-NHS ester
TRC-D194965-1MGDBCO-NHS Ester
4529-AATDBCO NHS Ester
445820-01DBCO-NHS Ester
MBS9022248-01DBCO-NHS ester
TRC-D194965-50MGDBCO-NHS Ester
BUP10426-01DBCO-NHS ester

Popular Products