DBCO-NHS ester 3

• Target :

  ADC Linker

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Bioactivity :

  DBCO-NHS ester 3 (Compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (ADC) . It is a derivative of Dibenzylcyclooctyne (DBCO) resulting from the activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC) [1][2].

• Smiles :

  O=C(ON1C(=O)CCC1=O)CCCC(=O)N2C=3C=CC=CC3C#CC=4C=CC=CC4C2

• Molecular Formula :

  C24H20N2O5

• Molecular Weight :

  416.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1393350-27-0