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STX-0119

CAT: 0804-HY-103692-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103692-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
STX-0119 is a selective, orally active STAT3 dimerization inhibitor. STX-0119 inhibits STAT3 transcription with an IC50 of 74 μM[1].
CAS Number
851095-32-4
UNSPSC
12352005
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stx-0119.html
Concentration
10mM
Purity
98.40
Solubility
DMSO : 13.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC(C2=CC=CC=C2)=NC3=C1C=CC=C3)NC4=NN=C(C5=CC=CO5)O4
Molecular Formula
C22H14N4O3
Molecular Weight
382.37
References & Citations
[1]Matsuno K, et al. Identification of a New Series of STAT3 Inhibitors by Virtual Screening. ACS Med Chem Lett. 2010 Jul 13;1 (8) :371-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT3

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