8-Aminoadenine

• Description:

  8-Aminoadenine is an adenine receptor ligand, with a Ki of 6.51 μM at the human binding site[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  NAChR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/8-aminoadenine.html

• Purity:

  98.34

• Solubility:

  1 M HCl : 0.5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  NC1=C2N=C(N)NC2=NC=N1

• Molecular Formula:

  C5H6N6

• Molecular Weight:

  150.14

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Thomas Borrmann, et al. Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family. J Med Chem. 2009 Oct 8;52 (19) :5974-89.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [28128-33-8]