Pyrene azide 3

• Description :

  Pyrene azide 3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Pyrene azide 3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• UNSPSC :

  12352005

• Target :

  PROTAC Linkers

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/pyrene-azide-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NCCOCCOCCN=[N+]=[N-])CCCC1=C(C2=C34)C=CC4=CC=CC3=CC=C2C=C1

• Molecular Formula :

  C26H28N4O3

• Molecular Weight :

  444.53

• References & Citations :

  [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-1014.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PEG Linkers

• CAS Number :

  [2252168-06-0]