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Pyrene-PEG2-azide

CAT: 0804-HY-141092-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-141092-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pyrene-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Pyrene-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
CAS Number
2135330-58-2
UNSPSC
12352005
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pyrene-peg2-azide.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCN=[N+]=[N-])C1=CC=C2C=CC3=CC=CC4=CC=C1C2=C43
Molecular Formula
C23H22N4O3
Molecular Weight
402.45
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

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