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α-Conotoxin Bt1.8

CAT: 0804-HY-P5850Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-P5850Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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UNSPSC Description
α-Conotoxin Bt1.8 is a potent α6/α3β2β3 and α3β2 nAChRs inhibitor with IC50s of 2.1 nM and 9.4 nM against rat α6/α3β2β3 and α3β2, respectively[1].
Target Antigen
nAChR
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C(CN)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H]2C)=O)CCC1)=O)CC(N)=O)=O)CO)=O)CSSC[C@H](NC3=O)C(N)=O)=O)CSSC[C@H](NC2=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N4[C@H](C(N[C@H](C(N[C@H]3CCC(N)=O)=O)CC(N)=O)=O)CCC4)=O)CC(N)=O)=O)CC(N)=O)=O)CC(C)C)=O)[C@H](CC)C)=O
Molecular Weight
1645.86
References & Citations
[1]Ning H, et al. α-Conotoxin Bt1.8 from Conus betulinus selectively inhibits α6/α3β2β3 and α3β2 nicotinic acetylcholine receptor subtypes. J Neurochem. 2021 Oct;159(1):90-100.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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