SB-649915

• Description:

  SB-649915 is a potent 5-HT1A/1B autoreceptor antagonist, with the pKi values of 8.6, 8.0, respectively and 5-HT reuptake inhibitor in native tissue systems and palys an important role in antidepressant research[1].

• UNSPSC:

  12352005

• Target:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sb-649915.html

• Smiles:

  O=C1COC2=CC=C(CC3CCN(CCOC4=C5C=CC(C)=NC5=CC=C4)CC3)C=C2N1

• Molecular Formula:

  C26H29N3O3

• Molecular Weight:

  431.53

• References & Citations:

  [1]Claire Scott, et al. SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue. Eur J Pharmacol. 2006 Apr 24;536 (1-2) :54-61.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [420785-70-2]