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Serotonin (hydrochloride)

CAT: 0804-HY-B1473-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1473-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
CAS Number
153-98-0
Product Name Alternative
5-Hydroxytryptamine (hydrochloride) ; 5-HT (hydrochloride)
UNSPSC
12352005
Hazard Statement
H301, H361
Target
5-HT Receptor; COMT; Endogenous Metabolite
Type
Natural Products
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Serotonin_hydrochloride.html
Concentration
10mM
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
OC1=CC2=C(NC=C2CCN)C=C1.[H]Cl
Molecular Formula
C10H13ClN2O
Molecular Weight
212.68
Precautions
H301, H361
References & Citations
[1]Tsao D, et al. Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity. Mol Pain. 2012 Apr 13;8:25.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite; Microbial Metabolite; MUC4
Citation 01
Authorea. September 19, 2022.|Behav Brain Res. 2025 May 7:115620.|Biochem Biophys Res Commun. 2025 Sep 19:785:152676.|bioRxiv. 2023 Oct 13.|bioRxiv. 2024 November 03.|bioRxiv. 2025 Sep 28.|Food Res Int. 2025 Aug:214:116675.|Immunity. 2025 Aug 12:S1074-7613 (25) 00314-0.|J Dent Sci. 2025 Apr 15.|J Immunother Cancer. 2021 Jul;9 (7) :e002383.|Nature. 2025 Jul;643 (8070) :192-200.|Res Sq. 2024 Jun 11.|Research Square Preprint. 2023 Dec 28.|SSRN. 2025 Apr 24.|bioRxiv. 2024 November 03.|bioRxiv. 2025 Oct 14.|Cell Stem Cell. 2025 May 1;32 (5) :778-794.e10.|Curr Res Food Sci. 2024 Apr 26:8:100754.|Int J Mol Sci. 2022 Oct 17;23 (20) :12420.|iScience. 2025 Jun 18;28 (7) :112931.|iScience. 2025 Nov 18.|J Exp Clin Cancer Res. 2024 Oct 10;43 (1) :284.|Neurosci Bull. 2025 Jul;41 (7) :1229-1245.

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