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Sirtuin-IN-2

CAT: 0804-HY-168681Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-168681Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sirtuin-IN-2 (compound 20) is an inhibitor of Sirtuin5, which is a key target for leukemia and breast cancer[1].
UNSPSC
12352211
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sirtuin-in-2.html
Smiles
S=C(NCCC(O)=O)NCCCC[C@H](NC(OCC1=CC=CC=C1)=O)C(N[C@@H](CCCNC(N)=N)C(NCCCC)=O)=O
Molecular Formula
C28H46N8O6S
Molecular Weight
622.78
References & Citations
[1]Hansen TN, et al. Mechanism-based inactivators of sirtuin 5: A focused structure-activity relationship study. Bioorg Med Chem Lett. 2025 Jan 1;115:130017.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT5

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