Sirtuin-IN-2

• Description :

  Sirtuin-IN-2 (compound 20) is an inhibitor of Sirtuin5, which is a key target for leukemia and breast cancer[1].

• UNSPSC :

  12352211

• Target :

  Sirtuin

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/sirtuin-in-2.html

• Smiles :

  S=C(NCCC(O)=O)NCCCC[C@H](NC(OCC1=CC=CC=C1)=O)C(N[C@@H](CCCNC(N)=N)C(NCCCC)=O)=O

• Molecular Formula :

  C28H46N8O6S

• Molecular Weight :

  622.78

• References & Citations :

  [1]Hansen TN, et al. Mechanism-based inactivators of sirtuin 5: A focused structure-activity relationship study. Bioorg Med Chem Lett. 2025 Jan 1;115:130017.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  SIRT5