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Chromanol 293B

CAT: 0804-HY-108575-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-108575-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Chromanol 293B is a selective blocker of the slow delayed rectifier K+ current (IKs) with IC50 of 1-10 μM and a weak inhibitor of KATP channel. Chromanol 293B also blocks the CFTR chloride current with an IC50 of 19 μM[1].
CAS Number
163163-23-3
UNSPSC
12352005
Hazard Statement
H302+H312+H332
Target
CFTR; Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/chromanol-293b.html
Purity
99.2
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CCS(N([C@H]1C2=CC(C#N)=CC=C2OC(C)([C@@H]1O)C)C)(=O)=O
Molecular Formula
C15H20N2O4S
Molecular Weight
324.40
Precautions
H302+H312+H332
References & Citations
[1]Bachmann A, Quast U, Russ U. Chromanol 293B, a blocker of the slow delayed rectifier K+ current (IKs), inhibits the CFTR Cl- current. Naunyn Schmiedebergs Arch Pharmacol. 2001 Jun;363 (6) :590-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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