Products for Research Use Only
RegisterLogin

Chroman 1

CAT: 0804-HY-15392-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-15392-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Chroman 1 is a highly potent and selective ROCK inhibitor. Chroman 1 is more potent against ROCK2 (IC50=1 pM) than ROCK1 (IC50=52 pM) . Chroman 1 also has inhibitory activity against MRCK, with an IC50 of 150 nM[1][2].
CAS Number
1273579-40-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
COVID-19-anti-virus
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/chroman-1.html
Purity
99.42
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C([C@@H]1COC2=CC=C(OC)C=C2C1)NC3=CC=C(C4=CNN=C4)C=C3OCCN(C)C
Molecular Formula
C24H28N4O4
Molecular Weight
436.50
Precautions
H302, H315, H319
References & Citations
[1]Yen Ting Chen, et al. Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitors. Med.Chem.Commun., 2011, 2, 73-75.|[2]Yu Chen, et al. A Versatile Polypharmacology Platform Promotes Cytoprotection and Viability of Human Pluripotent and Differentiated Cells. bioRxiv 815761.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ROCK1; ROCK2

Related Products

CatalogName
HY-44135-017-Hydroxy-3- (4-hydroxybenzylidene) chroman-4-one
HY-132519S-01Delta-Tocopherol-5-formyl-chroman-5-carboxylic acid-d3
HY-N2296(2R,3R) -3,7-Dihydroxy-2- (4-hydroxyphenyl) -5-methoxy-8- (3-methylbut-2-en-1-yl) chroman-4-one
HY-N89678-Glucosyl-5,7-dihydroxy-2- (1-methylpropyl) chromone
HY-N6838-011,1,1,1-Kestohexaose
HY-157129AMPK-α1β1γ1 activator 1
HY-1336231,1,1-Tribromoacetone
HY-W400839R2-Chloro-1- (5H-chromeno[2,3-b]pyridin-7-yl) propan-1-one (Standard)
HY-N106922- (trans-1,4-Dihydroxy-cyclohexyl) -5,7-dihydroxy-chromone
HY-149536TWIK-1/TREK-1-IN-1

Alternative Products

CatalogName
MBS3615264-01Chroman 1
FCA74597-01Chroman-6-carbaldehyde
266276-012-Bromomethyl-chroman
A15045-50Chroman 1 50mg
A15045-10Chroman 1 10mg
BUP23471-01Chroman-8-carboxamide
OR181072- (Bromomethyl) chroman
OR45040Chroman-6-carboxaldehyde
OR87659-01Chroman-7-ol
GTR19185142-01Chroman 1 dihydrochloride

Popular Products